GABAA receptor agent 4
Modify Date: 2025-08-25 10:29:59
GABAA receptor agent 4 structure
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Common Name | GABAA receptor agent 4 | ||
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| CAS Number | 2035203-91-7 | Molecular Weight | 272.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H24N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GABAA receptor agent 4GABAA receptor agent 4 (compound 1e) is a potent γ-GABAAR antagonist with an Ki of 0.18 µM. GABAA receptor agent 4 efficiently rescues inhibition of T cell proliferation. GABAA receptor agent 4 has the immunomodulatory potential[1]. |
| Name | GABAA receptor agent 4 |
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| Description | GABAA receptor agent 4 (compound 1e) is a potent γ-GABAAR antagonist with an Ki of 0.18 µM. GABAA receptor agent 4 efficiently rescues inhibition of T cell proliferation. GABAA receptor agent 4 has the immunomodulatory potential[1]. |
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| Related Catalog | |
| Target |
Ki: 0.18 µM (γ-GABAAR)[1] |
| In Vitro | GABAA receptor agent 4 (compound 1e) shows antagonist activity with IC50s of 4.95, 0.195, 0.250, 1.95, 2.18, 7.56, 0.56, 0.54 µM for α1β2δ, α4β1δ, α4β2δ, α6β2δ, α1β2γ2, α2β2γ2, α3β2γ2, α5β2γ2 subtypes, respectively[1]. GABAA receptor agent 4 (50 µM; 96 h) rescues inhibition of proliferation induced by alprazolam in both human PBMC and mouse splenocytes populations with minimal cell toxicity[1]. |
| References |
| Molecular Formula | C17H24N2O |
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| Molecular Weight | 272.39 |