GABAA receptor agent 1

Modify Date: 2024-04-03 20:07:47

GABAA receptor agent 1 structure	Common Name	GABAA receptor agent 1
	CAS Number	1571-87-5	Molecular Weight	273.674
	Density	1.5±0.1 g/cm3	Boiling Point	502.1±56.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₈ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	257.5±31.8 °C

Use of GABAA receptor agent 1

GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1].

Name	2-(4-Chlorophenyl)-6-nitro-1H-benzimidazole
Synonym	More Synonyms

Description	GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
In Vivo	GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats[1].
References	[1]. Jain P, et al. Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity. Arch Pharm Res. 2010 Jul;33(7):971-80.

Density	1.5±0.1 g/cm3
Boiling Point	502.1±56.0 °C at 760 mmHg
Molecular Formula	C₁₃H₈ClN₃O₂
Molecular Weight	273.674
Flash Point	257.5±31.8 °C
Exact Mass	273.030518
LogP	3.21
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.719
InChIKey	KJXNOHLXULKUIZ-UHFFFAOYSA-N
SMILES	O=[N+]([O-])c1ccc2nc(-c3ccc(Cl)cc3)[nH]c2c1

Hazard Codes	Xi

2-(4-Chlorophenyl)-6-nitro-1H-benzimidazole

MFCD05256114

MFCD00616523

1H-Benzimidazole, 2-(4-chlorophenyl)-6-nitro-

Get all suppliers and price by the below link: