GABAA receptor agent 7
Modify Date: 2025-08-26 18:58:02
GABAA receptor agent 7 structure
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Common Name | GABAA receptor agent 7 | ||
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| CAS Number | 2376841-18-6 | Molecular Weight | 336.78 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H13ClN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GABAA receptor agent 7GABAA receptor agent 7 (compoud 5c) is a potent GABAA receptor positive modulator. GABAA receptor agent 7 shows anticonvulsant activity in vitro and in vivo with low neurotoxicity. GABAA receptor agent 7 has the potential for the research of epilepsy[1]. |
| Name | GABAA receptor agent 7 |
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| Description | GABAA receptor agent 7 (compoud 5c) is a potent GABAA receptor positive modulator. GABAA receptor agent 7 shows anticonvulsant activity in vitro and in vivo with low neurotoxicity. GABAA receptor agent 7 has the potential for the research of epilepsy[1]. |
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| Related Catalog | |
| In Vitro | GABAA receptor agent 7 (compoud 5c) shows anticonvulsant activity with an IC50 of 0.452 µM in 4-AP induced hyper-excitability Model[1]. GABAA receptor agent 7 (0.01-100 µM; 0-140 s) increases GABA-induced activation of GABAA1 receptor in a dose-dependent manner with EC50 3.08 µM[1]. |
| In Vivo | GABAA receptor agent 7 shows anticonvulsant activity in mice with an ED50 of 31.81 mg/kg and an TD50 of 547.89 mg/kg[1]. GABAA receptor agent 7 specifically attenuates PTZ-induced seizures but not MES-induced seizures in mice[1]. |
| References |
| Molecular Formula | C18H13ClN4O |
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| Molecular Weight | 336.78 |