Steroid sulfatase-IN-2
Modify Date: 2024-07-17 17:38:28
Steroid sulfatase-IN-2 structure
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Common Name | Steroid sulfatase-IN-2 | ||
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| CAS Number | 2413880-39-2 | Molecular Weight | 350.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H22N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Steroid sulfatase-IN-2Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer[1]. |
| Name | Steroid sulfatase-IN-2 |
|---|
| Description | Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer[1]. |
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| Related Catalog | |
| Target |
IC50：109.5 nM (STS)[1] |
| In Vitro | Steroid sulfatase-IN-2 (compound 1h, 0.001-10 μM, 1 h) inhibits STS in the lysate of JEG-3 cells, with an IC50 value of 109.5 nM[1]. Steroid sulfatase-IN-2 (1-1 μM, 20 h) inhibits STS in a whole-cell assay against JEG-3 cells, with an IC50 value of 13.6 nM[1]. Steroid sulfatase-IN-2 (0.01-100 μM, 5 days) shows dose-dependent antiproliferative activity against T-47D estrogen-dependent breast cancer cells[1]. Cell Viability Assay[1] Cell Line: T-47D cells Concentration: 0.01-100 μM Incubation Time: 5 days Result: Inhibited cell proliferation with an IC50 value of 5.78 μM. |
| References |
| Molecular Formula | C17H22N2O4S |
|---|---|
| Molecular Weight | 350.43 |