2413880-53-0

2413880-53-0 structure

Name: Steroid sulfatase-IN-3
Chemical Name: Steroid sulfatase-IN-3
CAS Number: 2413880-53-0
Molecular Formula: C₁₇H₂₁ClN₂O₄S
Molecular Weight: 384.88
Catalog: Research Areas Cancer
Create Date: 2022-08-16 10:19:10
Modify Date: 2025-08-25 19:16:36
Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM[1].

Name	Steroid sulfatase-IN-3

Description	Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 25.8 nM (STS, in JEG-3 cell lysate), 150.0 nM (STS, in JEG-3 cells)[1]
References	[1]. El-Gamal MI, et al. A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation. Bioorg Med Chem. 2020 Apr 15;28(8):115406.

Molecular Formula	C₁₇H₂₁ClN₂O₄S
Molecular Weight	384.88