357618-26-9
357618-26-9 structure
- Name: RNase L-IN-2
- Chemical Name: 2-(3-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
- CAS Number: 357618-26-9
- Molecular Formula: C16H14N2O2S
- Molecular Weight: 298.360
- Create Date: 2020-01-11 19:07:26
- Modify Date: 2023-01-16 10:19:16
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RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.
| Name | 2-(3-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one |
|---|---|
| Synonyms |
[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 5,6,7,8-tetrahydro-2-(3-hydroxyphenyl)-
2-(3-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one MFCD02212163 |
| Description | RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations. |
|---|---|
| References | References 1. Thakur CS, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9585-90. View Related Products by Target Other Targets |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C16H14N2O2S |
| Molecular Weight | 298.360 |
| Exact Mass | 298.077606 |
| LogP | 3.09 |
| Index of Refraction | 1.781 |
| Hazard Codes | Xi |
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