Steroid sulfatase-IN-1
Modify Date: 2025-09-21 18:58:30
Steroid sulfatase-IN-1 structure
|
Common Name | Steroid sulfatase-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2403716-19-6 | Molecular Weight | 385.23 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H10Cl2N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Steroid sulfatase-IN-1Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 µM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1]. |
| Name | Steroid sulfatase-IN-1 |
|---|
| Description | Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 µM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.71 µM (Steroid sulfatase)[1] |
| In Vivo | Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51%[1]. Animal Model: 67NR mouse[1] Dosage: 50 mg/kg Administration: P.o. Result: Showed significant antitumor activity with the TGI value of 51%. |
| References |
| Molecular Formula | C14H10Cl2N4O3S |
|---|---|
| Molecular Weight | 385.23 |
| InChIKey | LVZFTBZGLNBDFP-UHFFFAOYSA-N |
| SMILES | NS(=O)(=O)Oc1ccc(-c2cn(-c3cc(Cl)cc(Cl)c3)nn2)cc1 |