CDK4/6-IN-6

Modify Date: 2024-01-07 21:14:02

CDK4/6-IN-6 structure	Common Name	CDK4/6-IN-6
	CAS Number	2380321-51-5	Molecular Weight	463.93
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₇ClFN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK4/6-IN-6

CDK4/6-IN-6 (example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1].

Name	CDK4/6-IN-6

Description	CDK4/6-IN-6 (example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	Cdk4/cyclin D1:0.6 nM (Ki) cdk6/cyclin D3:13.9 nM (Ki)
In Vitro	CDK4/6-IN-6 (example A94) has IC50s of 38.5 nM and 144.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3 using phospho-Rb S795 ELISA assays in JEKO-1 and MV4-1 1 cells[1].
References	[1]. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

Molecular Formula	C₂₂H₂₇ClFN₅O₃
Molecular Weight	463.93

DC Chemicals Limited
China
Product Name: CDK4/6-IN-6
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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