CDK4/6-IN-6
Modify Date: 2025-08-25 11:21:45
CDK4/6-IN-6 structure
|
Common Name | CDK4/6-IN-6 | ||
|---|---|---|---|---|
| CAS Number | 2380321-51-5 | Molecular Weight | 463.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H27ClFN5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK4/6-IN-6CDK4/6-IN-6 (example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. |
| Name | CDK4/6-IN-6 |
|---|
| Description | CDK4/6-IN-6 (example A94) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Cdk4/cyclin D1:0.6 nM (Ki) cdk6/cyclin D3:13.9 nM (Ki) |
| In Vitro | CDK4/6-IN-6 (example A94) has IC50s of 38.5 nM and 144.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3 using phospho-Rb S795 ELISA assays in JEKO-1 and MV4-1 1 cells[1]. |
| References |
| Molecular Formula | C22H27ClFN5O3 |
|---|---|
| Molecular Weight | 463.93 |