Name | 2-{[(1-{6-[(9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl}-4-piperidinyl)methyl]amino}ethanol |
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Synonyms |
Ethanol, 2-[[[1-[6-[(9-cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-4-piperidinyl]methyl]amino]-
2-{[(1-{6-[(9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl}-4-piperidinyl)methyl]amino}ethanol |
Description | CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1]. |
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Related Catalog | |
Target |
CDK4:13 nM (IC50) CDK6 |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 729.5±70.0 °C at 760 mmHg |
Molecular Formula | C27H33FN8O |
Molecular Weight | 504.602 |
Flash Point | 395.0±35.7 °C |
Exact Mass | 504.276123 |
LogP | 1.86 |
Vapour Pressure | 0.0±2.5 mmHg at 25°C |
Index of Refraction | 1.735 |