2380321-50-4
2380321-50-4 structure
- Name: CDK4/6-IN-5
- Chemical Name: CDK4/6-IN-5
- CAS Number: 2380321-50-4
- Molecular Formula: C22H28ClFN6O4S
- Molecular Weight: 527.01
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2021-10-30 00:13:50
- Modify Date: 2024-01-02 12:02:27
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CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93).
| Name | CDK4/6-IN-5 |
|---|
| Description | CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93). |
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| Related Catalog | |
| In Vitro | The CDK4 and CDK6 cell-based IC50s of CDK4/6-IN-5 in JEKO-1 and MV4-1 1 cells are 23.8 and 61.4 nM, respectively[1]. |
| References |
| Molecular Formula | C22H28ClFN6O4S |
|---|---|
| Molecular Weight | 527.01 |