CDK4/6-IN-5

Modify Date: 2024-01-02 12:02:27

CDK4/6-IN-5 structure	Common Name	CDK4/6-IN-5
	CAS Number	2380321-50-4	Molecular Weight	527.01
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₈ClFN₆O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK4/6-IN-5

CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93).

Name	CDK4/6-IN-5

Description	CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
In Vitro	The CDK4 and CDK6 cell-based IC50s of CDK4/6-IN-5 in JEKO-1 and MV4-1 1 cells are 23.8 and 61.4 nM, respectively[1].
References	[1]. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

Molecular Formula	C₂₂H₂₈ClFN₆O₄S
Molecular Weight	527.01

DC Chemicals Limited
China
Product Name: CDK4/6-IN-5
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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