2688098-02-2

2688098-02-2 structure
2688098-02-2 structure
  • Name: CDK4/6-IN-9
  • Chemical Name: CDK4/6-IN-9
  • CAS Number: 2688098-02-2
  • Molecular Formula: C22H23FN8
  • Molecular Weight: 418.47
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2022-07-04 10:53:20
  • Modify Date: 2025-08-26 17:27:46
  • CDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 has the potential for multiple myeloma (MM) research[1].

Name CDK4/6-IN-9
Description CDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 has the potential for multiple myeloma (MM) research[1].
Related Catalog
Target

CDK6/cyclinD1:905 nM (IC50)

CDK4/cyclinD1

References

[1]. Kai Yuan, et al. Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma. Eur J Med Chem. 2022 Jan 15;228:114024.

Molecular Formula C22H23FN8
Molecular Weight 418.47
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