Desmorpholinyl Quizartinib-PEG2-COOH

Modify Date: 2024-01-02 16:15:56

Desmorpholinyl Quizartinib-PEG2-COOH structure	Common Name	Desmorpholinyl Quizartinib-PEG2-COOH
	CAS Number	2292116-14-2	Molecular Weight	607.68
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₃N₅O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM [1].

Name	Desmorpholinyl Quizartinib-PEG2-COOH

Description	Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM [1].
Related Catalog	Research Areas >> Cancer
References	[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.

Molecular Formula	C₃₀H₃₃N₅O₇S
Molecular Weight	607.68

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: Desmorpholinyl Quizartinib-PEG2-COOH
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥8500/50 mg

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Desmorpholinyl Quizartinib-PEG2-COOH

Use of Desmorpholinyl Quizartinib-PEG2-COOH

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