756525-98-1
756525-98-1 structure
- Name: Mal-amido-PEG2-C2-acid
- Chemical Name: MAL-PEG2-COOH
- CAS Number: 756525-98-1
- Molecular Formula: C14H20N2O7
- Molecular Weight: 328.318
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-09-22 11:11:15
- Modify Date: 2024-01-05 19:21:13
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Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | MAL-PEG2-COOH |
|---|---|
| Synonyms |
Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-
3-[2-(2-{[3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]propanoic acid |
| Description | Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 617.3±55.0 °C at 760 mmHg |
| Molecular Formula | C14H20N2O7 |
| Molecular Weight | 328.318 |
| Flash Point | 327.2±31.5 °C |
| Exact Mass | 328.127045 |
| LogP | -1.54 |
| Vapour Pressure | 0.0±3.8 mmHg at 25°C |
| Index of Refraction | 1.530 |
| Storage condition | 2-8°C |