Desmorpholinyl Navitoclax-NH-Me

Modify Date: 2024-01-20 09:29:08

Desmorpholinyl Navitoclax-NH-Me Structure
Desmorpholinyl Navitoclax-NH-Me structure
Common Name Desmorpholinyl Navitoclax-NH-Me
CAS Number 2365172-82-1 Molecular Weight 918.55
Density N/A Boiling Point N/A
Molecular Formula C44H51ClF3N5O5S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desmorpholinyl Navitoclax-NH-Me


Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557)[1][2].

 Names

Name Desmorpholinyl Navitoclax-NH-Me

 Desmorpholinyl Navitoclax-NH-Me Biological Activity

Description Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557)[1][2].
Related Catalog
References

[1]. Guangrong Zheng, et al. Agents de dégradation de protéines bcl-2 pour le traitement du cancer. WO2019144117A1.

 Chemical & Physical Properties

Molecular Formula C44H51ClF3N5O5S3
Molecular Weight 918.55

 Safety Information

Hazard Codes Xi
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