2365172-82-1

2365172-82-1 structure

Name: Desmorpholinyl Navitoclax-NH-Me
Chemical Name: Desmorpholinyl Navitoclax-NH-Me
CAS Number: 2365172-82-1
Molecular Formula: C₄₄H₅₁ClF₃N₅O₅S₃
Molecular Weight: 918.55
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2020-08-11 10:54:08
Modify Date: 2025-08-25 07:06:54
Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557)[1][2].

Name	Desmorpholinyl Navitoclax-NH-Me

Description	Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557)[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
References	[1]. Guangrong Zheng, et al. Agents de dégradation de protéines bcl-2 pour le traitement du cancer. WO2019144117A1.

Molecular Formula	C₄₄H₅₁ClF₃N₅O₅S₃
Molecular Weight	918.55

Hazard Codes	Xi