F-PEG2-COOH

Modify Date: 2024-01-09 22:47:25

F-PEG2-COOH Structure
F-PEG2-COOH structure
Common Name F-PEG2-COOH
CAS Number 2383964-72-3 Molecular Weight 166.15
Density N/A Boiling Point N/A
Molecular Formula C6H11FO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of F-PEG2-COOH


F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name F-PEG2-COOH

 F-PEG2-COOH Biological Activity

Description F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C6H11FO4
Molecular Weight 166.15