CYP4A11/CYP4F2-IN-2

Modify Date: 2025-08-26 19:27:56

CYP4A11/CYP4F2-IN-2 Structure
CYP4A11/CYP4F2-IN-2 structure
 Common Name CYP4A11/CYP4F2-IN-2
CAS Number 2280834-99-1 Molecular Weight 361.44
Density N/A Boiling Point N/A
Molecular Formula C19H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CYP4A11/CYP4F2-IN-2


CYP4A11/CYP4F2-IN-2 (compound 15) is an orally available inhibitor of CYP4A11/4F2 with IC50s of 120 nM and 220 nM, respectively. CYP4A11/CYP4F2-IN-2 inhibits 20-HETE production in rat kidney and has potential inhibitory effects on diabetic nephropathy and autosomal dominant polycystic kidney disease[1].

 Names

Name CYP4A11/CYP4F2-IN-2

 CYP4A11/CYP4F2-IN-2 Biological Activity

Description CYP4A11/CYP4F2-IN-2 (compound 15) is an orally available inhibitor of CYP4A11/4F2 with IC50s of 120 nM and 220 nM, respectively. CYP4A11/CYP4F2-IN-2 inhibits 20-HETE production in rat kidney and has potential inhibitory effects on diabetic nephropathy and autosomal dominant polycystic kidney disease[1].
Related Catalog
Target

CYP4A11, CYP4F2[1]

References

[1]. Kawamura M et al. Introduction of a carboxylic acid group into pyrazolylpyridine derivatives increased selectivity for inhibition of the 20-HETE synthase CYP4A11/4F2[J]. Bioorganic & Medicinal Chemistry, 2023: 117505.

 Chemical & Physical Properties

Molecular Formula C19H27N3O4
Molecular Weight 361.44
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here
Related Compounds: More...
CYP4A11/CYP4F2-IN-2
2126874-77-7
CYP4A11/CYP4F2-IN-1
502654-40-2
SARS-CoV-IN-2
888958-26-7
Lp-PLA2-IN-2
2071636-15-0
HIF-2α-IN-2
1672666-82-8
HDAC1,2-IN-2
937727-03-2
Androgen receptor-IN-2
2416716-62-4
RNase L-IN-2
357618-26-9
CBP/EP300-IN-2
2158265-96-2
Mutated EGFR-IN-2
2050906-97-1
Poly(oxy-1,2-ethanediyl), I+/--[(9R,20Z)-6-hydroxy-6-oxido-1,12-dioxo-9-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-20-en-1-yl]-I-methoxy-
226940-29-0
I(2)-D-Glucopyranose, 1-[(1S,4aS,6S,7R,7aS)-6-[(2,3-dihydroxybenzoyl)oxy]-1-(I(2)-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-7-methylcyclopenta[c]pyran-4-carboxylate]
157722-22-0
5-(Butylamino)-2-[[2-(dimethylamino)ethoxy]carbonyl]phenyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
896442-33-4
3-[[6-O-(6-Deoxy-I+/--L-mannopyranosyl)-I(2)-D-glucopyranosyl]oxy]-7-(2,3-dihydroxypropoxy)-2-[4-(2,3-dihydroxypropoxy)-3-hydroxyphenyl]-5-hydroxy-4H-1-benzopyran-4-one
47887-05-8
5-[[4-[[2-[Bis(2-aminoethyl)amino]ethyl]amino]-6-chloro-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[2-(1-sulfo-2-naphthalenyl)diazenyl]-2,7-naphthalenedisulfonic acid
1160628-60-3
Hexanoic acid, 6-[(2-methyl-1-oxo-2-propenyl)oxy]-, 3-[2,2-dimethyl-3-[[6-[(2-methyl-1-oxo-2-propenyl)oxy]-1-oxohexyl]oxy]-1-oxopropoxy]-2,2-dimethylpropyl ester
128940-91-0
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(oxan-2-yloxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
104992-58-7
2-[2-[6-[[4-[[(4-Aminophenyl)methyl]methylamino]-6-chloro-1,3,5-triazin-2-yl]amino]-1-hydroxy-3,5-disulfo-2-naphthalenyl]diazenyl]-1,5-naphthalenedisulfonic acid
1185739-38-1
1-[7-[Ethyl[2-methyl-3-(trimethylsilyl)propyl]amino]heptyl]-3,5-bis[6-[ethyl[2-methyl-3-(trimethylsilyl)propyl]amino]hexyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
1184933-17-2
4-[(1E)-2-[2,6-Dihydroxy-3-[(1E)-2-(2-hydroxy-5-nitrophenyl)diazenyl]phenyl]diazenyl]-5-hydroxy-1-[(1E)-2-(4-nitrophenyl)diazenyl]-2,7-naphthalenedisulfonic acid
1185250-55-8
Chemsrc provides CYP4A11/CYP4F2-IN-2(CAS#:2280834-99-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CYP4A11/CYP4F2-IN-2 are included as well.>> amp version: CYP4A11/CYP4F2-IN-2

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved