Grp94 Inhibitor-1

Modify Date: 2025-08-30 12:32:52

Grp94 Inhibitor-1 structure	Common Name	Grp94 Inhibitor-1
	CAS Number	2234897-35-7	Molecular Weight	352.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₈N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Grp94 Inhibitor-1

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].

Name	Grp94 Inhibitor-1

Description	Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	GRP94:2 nM (IC50)
References	[1]. Jiang F, et al. Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis. J Med Chem. 2018 Nov 8;61(21):9513-9533.

Molecular Formula	C₂₂H₂₈N₂O₂
Molecular Weight	352.47
InChIKey	JMGDXIHGWTVBMX-UHFFFAOYSA-N
SMILES	CC(C)c1ccc(-c2ccc(NC3CCC(O)CC3)c(C(N)=O)c2)cc1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Grp94 Inhibitor-1
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Purity: 98.0%
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