2234897-35-7

2234897-35-7 structure

2234897-35-7 structure

Name: Grp94 Inhibitor-1
Chemical Name: Grp94 Inhibitor-1
CAS Number: 2234897-35-7
Molecular Formula: C₂₂H₂₈N₂O₂
Molecular Weight: 352.47
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2019-06-29 17:42:05
Modify Date: 2024-01-07 16:51:09
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].

Name	Grp94 Inhibitor-1

Description	Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	GRP94:2 nM (IC50)
References	[1]. Jiang F, et al. Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis. J Med Chem. 2018 Nov 8;61(21):9513-9533.

Molecular Formula	C₂₂H₂₈N₂O₂
Molecular Weight	352.47