SC 221409

Modify Date: 2024-01-12 19:10:15

SC 221409 Structure
SC 221409 structure
Common Name SC 221409
CAS Number 222035-13-4 Molecular Weight 395.231
Density 1.9±0.1 g/cm3 Boiling Point N/A
Molecular Formula C14H11BrN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SC 221409


CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].

 Names

Name 4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino ]benzenesulfonamide
Synonym More Synonyms

 SC 221409 Biological Activity

Description CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].
Related Catalog
Target

CDK2:60 nM (IC50)

References

[1]. S T Davis, et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science. 2001 Jan 5;291(5501):134-7.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Molecular Formula C14H11BrN4O3S
Molecular Weight 395.231
Exact Mass 393.973511
PSA 122.03000
LogP 2.53
Index of Refraction 1.769

 Synonyms

4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzenesulfonamide
4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]benzenesulfonamide
Benzenesulfonamide, 4-[(2Z)-2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
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