222035-13-4

222035-13-4 structure

Name: SC 221409
Chemical Name: 4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino ]benzenesulfonamide
CAS Number: 222035-13-4
Molecular Formula: C₁₄H₁₁BrN₄O₃S
Molecular Weight: 395.231
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2016-11-19 03:22:23
Modify Date: 2024-01-12 19:10:15
CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].

Name	4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino ]benzenesulfonamide
Synonyms	4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzenesulfonamide 4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]benzenesulfonamide Benzenesulfonamide, 4-[(2Z)-2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-

Description	CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK2:60 nM (IC50)
References	[1]. S T Davis, et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science. 2001 Jan 5;291(5501):134-7.