Azido-PEG5-CH2CO2-PFP

Modify Date: 2024-01-10 11:21:50

Azido-PEG5-CH2CO2-PFP Structure
Azido-PEG5-CH2CO2-PFP structure
Common Name Azido-PEG5-CH2CO2-PFP
CAS Number 2144777-92-2 Molecular Weight 487.38
Density N/A Boiling Point N/A
Molecular Formula C18H22F5N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-CH2CO2-PFP


Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG5-CH2CO2-PFP

 Azido-PEG5-CH2CO2-PFP Biological Activity

Description Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C18H22F5N3O7
Molecular Weight 487.38
Storage condition 2-8°C