Azido-PEG5-acid

Modify Date: 2024-01-02 19:54:36

Azido-PEG5-acid Structure
Azido-PEG5-acid structure
Common Name Azido-PEG5-acid
CAS Number 1425973-16-5 Molecular Weight 379.406
Density N/A Boiling Point N/A
Molecular Formula C13H25N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-acid


Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)).

 Names

Name Azido-PEG5-acid
Synonym More Synonyms

 Azido-PEG5-acid Biological Activity

Description Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)).
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zolotarskaya OY, et al. Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug. RSC Adv. 2015;5(72):58600-58608. Epub 2015 Jun 29.

 Chemical & Physical Properties

Molecular Formula C13H25N3O7
Molecular Weight 379.406
Exact Mass 379.195465
LogP -1.78
Storage condition 2-8°C

 Synonyms

1-Azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-
MFCD22056306