Azido-PEG5-Boc

Modify Date: 2024-01-10 12:23:32

Azido-PEG5-Boc Structure
Azido-PEG5-Boc structure
Common Name Azido-PEG5-Boc
CAS Number 1448451-72-6 Molecular Weight 377.433
Density N/A Boiling Point N/A
Molecular Formula C16H31N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-Boc


Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG5-CH2CO2t-butyl ester
Synonym More Synonyms

 Azido-PEG5-Boc Biological Activity

Description Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H31N3O7
Molecular Weight 377.433
Exact Mass 377.216187
LogP 0.40

 Synonyms

AZIDO-PEG5-CH2CO2TBU
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