356046-26-9

356046-26-9 structure

Name: Azido-PEG5-azide
Chemical Name: 1-azido-2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethane
CAS Number: 356046-26-9
Molecular Formula: C₁₂H₂₄N₆O₅
Molecular Weight: 332.35600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-04-01 13:39:54
Modify Date: 2024-04-02 16:53:18
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-azido-2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethane
Synonyms	bisazido hexaethylene glycol 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-azide Azido-PEG5-Azide 1,17-DIAZIDO-3,6,9,12,15-PENTAOXAHEPTADECANE

Description	Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.