1448451-72-6

1448451-72-6 structure

Name: Azido-PEG5-Boc
Chemical Name: Azido-PEG5-CH2CO2t-butyl ester
CAS Number: 1448451-72-6
Molecular Formula: C₁₆H₃₁N₃O₇
Molecular Weight: 377.433
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-10 02:41:28
Modify Date: 2024-01-10 12:23:32
Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG5-CH2CO2t-butyl ester
Synonyms	AZIDO-PEG5-CH2CO2TBU

Description	Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562