VU 0650786

Modify Date: 2024-01-10 15:06:32

VU 0650786 structure	Common Name	VU 0650786
	CAS Number	1809085-30-0	Molecular Weight	387.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₅ClFN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VU 0650786

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].

Name	VU0650786

Description	VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR3:392 nM (IC50)
References	[1]. Engers JL, et al. Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents. J Med Chem. 2015 Sep 24;58(18):7485-500.

Molecular Formula	C₁₈H₁₅ClFN₅O₂
Molecular Weight	387.80
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: VU 0650786
Price: $950.0/100mg $1900.0/250mg $3800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

VU 0650786 suppliers

VU 0650786 price

VU 0650786

Use of VU 0650786

Names

VU 0650786 Biological Activity

Chemical & Physical Properties