Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VU 0365114
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: VU 0365114
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: VU 0365114
Price: $600.0/100mg $1100.0/250mg $1950.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: VU 0365114
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

1208222-39-2

1208222-39-2 structure

1208222-39-2 structure

Name: VU 0365114
Chemical Name: 1-(4-Biphenylylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione
CAS Number: 1208222-39-2
Molecular Formula: C₂₂H₁₄F₃NO₃
Molecular Weight: 397.34700
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2017-02-24 01:58:19
Modify Date: 2025-08-26 19:16:22
VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.

Name	1-(4-Biphenylylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione

Description	VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Others
Target	EC50: 2.7 μM (mAChR M5)[1].
References	[1]. Bridges TM, et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22.

Molecular Formula	C₂₂H₁₄F₃NO₃
Molecular Weight	397.34700
Exact Mass	397.09300
PSA	46.61000
LogP	5.04670
Storage condition	2-8℃

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