VU 0365114

Modify Date: 2025-08-26 19:16:22

VU 0365114 Structure
VU 0365114 structure
 Common Name VU 0365114
CAS Number 1208222-39-2 Molecular Weight 397.34700
Density N/A Boiling Point N/A
Molecular Formula C22H14F3NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VU 0365114


VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.

 Names

Name 1-(4-Biphenylylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione

 VU 0365114 Biological Activity

Description VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.
Related Catalog
Target

EC50: 2.7 μM (mAChR M5)[1].

References

[1]. Bridges TM, et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22.

 Chemical & Physical Properties

Molecular Formula C22H14F3NO3
Molecular Weight 397.34700
Exact Mass 397.09300
PSA 46.61000
LogP 5.04670
Storage condition 2-8℃
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Chemsrc provides VU 0365114(CAS#:1208222-39-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of VU 0365114 are included as well.>> amp version: VU 0365114

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