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VU 0365114

Names

[ CAS No. ]:
1208222-39-2

[ Name ]:
VU 0365114

Biological Activity

[Description]:

VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mAChR
Signaling Pathways >> Neuronal Signaling >> mAChR
Research Areas >> Others

[Target]

EC50: 2.7 μM (mAChR M5)[1].


[References]

[1]. Bridges TM, et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22.


[Related Small Molecules]

Carbachol | Darifenacin HBr | Arecoline hydrobromide | Pirenzepine, Dihydrochloride | Glycopyrrolate | Imidafenacin | Benztropine Mesylate | Xanomeline oxalate | Batefenterol | Bethanechol chloride | Cevimeline hydrochloride hemihydrate | Otilonium Bromide | solifenacin | VU0467154 | Anisodamine

Chemical & Physical Properties

[ Molecular Formula ]:
C22H14F3NO3

[ Molecular Weight ]:
397.34700

[ Exact Mass ]:
397.09300

[ PSA ]:
46.61000

[ LogP ]:
5.04670

[ Storage condition ]:
2-8℃

Related Compounds