5-Hydroxyferulic acid

Modify Date: 2024-01-03 21:59:07

5-Hydroxyferulic acid Structure
5-Hydroxyferulic acid structure
Common Name 5-Hydroxyferulic acid
CAS Number 1782-55-4 Molecular Weight 210.18300
Density 1.44g/cm3 Boiling Point 449.1ºC at 760mmHg
Molecular Formula C10H10O5 Melting Point N/A
MSDS N/A Flash Point 182.8ºC

 Use of 5-Hydroxyferulic acid


5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

 Names

Name 5-hydroxyferulic acid
Synonym More Synonyms

 5-Hydroxyferulic acid Biological Activity

Description 5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].
Related Catalog
In Vitro The product of the alfalfa Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT) catalyzed methylation of 5-Hydroxyferulic acid is sinapic acid. 5-Hydroxyferulic acid O-methyltransferase activities (pkat mg-1 protein) in stem material from COMT downregulates transgenic alfalfa[1].
References

[1]. K Parvathi, et al. Substrate Preferences of O-methyltransferases in Alfalfa Suggest New Pathways for 3-O-methylation of Monolignols. Plant J. 2001 Jan;25(2):193-202.

[2]. S Maury, et al. Tobacco O-methyltransferases Involved in Phenylpropanoid Metabolism. The Different Caffeoyl-Coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferase Classes Have Distinct Substrate Specificities and Expression Patterns. Plant Physiol. 1999 Sep;121(1):215-24.

[3]. Inoue, et al. Substrate Preferences of Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferases in Developing Stems of Alfalfa (Medicago Sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82.

 Chemical & Physical Properties

Density 1.44g/cm3
Boiling Point 449.1ºC at 760mmHg
Molecular Formula C10H10O5
Molecular Weight 210.18300
Flash Point 182.8ºC
Exact Mass 210.05300
PSA 86.99000
LogP 1.20420
Vapour Pressure 7.49E-09mmHg at 25°C
Index of Refraction 1.664

 Safety Information

Hazard Codes Xi
HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

3-Methoxy-4,5-dihydroxy-zimtsaeure
5-Hydroxyferulic acid methyl ester
3-(3,4-Dihydroxy-5-methoxyphenyl)-2-propenoic acid 3-Methoxycaffeic acid 5-Hydroxyferulic acid
(E)-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enoic acid
5-Hydroxyferulic acid
4,5-dihydroxy-3-methoxycinnamic acid