(E)-5-Hydroxyferulic acid

Modify Date: 2025-08-27 10:04:44

(E)-5-Hydroxyferulic acid structure	Common Name	(E)-5-Hydroxyferulic acid
	CAS Number	110642-42-7	Molecular Weight	210.18300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₀O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (E)-5-Hydroxyferulic acid

(E)-5-Hydroxyferulic acid is the E-isomer of 5-hydroxyferulic acid (HY-133068). 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat[1][2][3].

Name	3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enoic acid
Synonym	More Synonyms

Description	(E)-5-Hydroxyferulic acid is the E-isomer of 5-hydroxyferulic acid (HY-133068). 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat[1][2][3].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> COMT Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> COMT
References	[1]. Parvathi K, et al. Substrate preferences of O-methyltransferases in alfalfa suggest new pathways for 3-O-methylation of monolignols. Plant J. 2001 Jan;25(2):193-202. [2]. Maury S, et al. Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns. Plant Physiol. 1999 Sep;121(1):215-24. [3]. Inoue K, et al. Substrate preferences of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferases in developing stems of alfalfa (Medicago sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82.

Description

Related Catalog

Signaling Pathways >> Neuronal Signaling >> COMT

Research Areas >> Metabolic Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> COMT

References

[1]. Parvathi K, et al. Substrate preferences of O-methyltransferases in alfalfa suggest new pathways for 3-O-methylation of monolignols. Plant J. 2001 Jan;25(2):193-202.

[2]. Maury S, et al. Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns. Plant Physiol. 1999 Sep;121(1):215-24.

[3]. Inoue K, et al. Substrate preferences of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferases in developing stems of alfalfa (Medicago sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82.

Molecular Formula	C₁₀H₁₀O₅
Molecular Weight	210.18300
Exact Mass	210.05300
PSA	86.99000
LogP	1.20420

Malonic acid

CAS#:141-82-2

3,4-Dihydroxy-5...

CAS#:3934-87-0

~64%

(E)-5-Hydroxyfe...

CAS#:110642-42-7

Literature: Lam; Iiyama; Stone Phytochemistry, 1996 , vol. 41, # 6 p. 1507 - 1510

5-Bromovanillin

CAS#:2973-76-4

(E)-5-Hydroxyfe...

CAS#:110642-42-7

Literature: Lam; Iiyama; Stone Phytochemistry, 1996 , vol. 41, # 6 p. 1507 - 1510

Vanillin

CAS#:121-33-5

(E)-5-Hydroxyfe...

CAS#:110642-42-7

Literature: Lam; Iiyama; Stone Phytochemistry, 1996 , vol. 41, # 6 p. 1507 - 1510

Precursor 4
CAS#:141-82-2 Malonic acid CAS#:3934-87-0 3,4-Dihydroxy-5... CAS#:2973-76-4 5-Bromovanillin CAS#:121-33-5 Vanillin
DownStream 0

2-Propenoic acid,3-(3,4-dihydroxy-5-methoxyphenyl)-,(2E)

p-hydroxyferulic acid

5-hydroxyferulic acid

(E)-3,4-dihydroxy-5-methoxycinnamic acid

(E)-5-hydroxyferulic acid

4,5-Dihydroxy-3-methoxy-zimtsaeure (3-Methoxy-kaffeesaeure)

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(E)-5-Hydroxyferulic acid

Use of (E)-5-Hydroxyferulic acid

Names

(E)-5-Hydroxyferulic acid Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.