1782-55-4

1782-55-4 structure

Name: 5-Hydroxyferulic acid
Chemical Name: 5-hydroxyferulic acid
CAS Number: 1782-55-4
Molecular Formula: C₁₀H₁₀O₅
Molecular Weight: 210.18300
Catalog: Signaling Pathways Metabolic Enzyme/Protease COMT
Create Date: 2017-08-24 16:02:14
Modify Date: 2025-09-05 07:54:38
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

Name	5-hydroxyferulic acid
Synonyms	3-Methoxy-4,5-dihydroxy-zimtsaeure 5-Hydroxyferulic acid methyl ester 3-(3,4-Dihydroxy-5-methoxyphenyl)-2-propenoic acid 3-Methoxycaffeic acid 5-Hydroxyferulic acid (E)-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enoic acid 5-Hydroxyferulic acid 4,5-dihydroxy-3-methoxycinnamic acid

Description	5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Neuronal Signaling >> COMT Signaling Pathways >> Metabolic Enzyme/Protease >> COMT
In Vitro	The product of the alfalfa Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT) catalyzed methylation of 5-Hydroxyferulic acid is sinapic acid. 5-Hydroxyferulic acid O-methyltransferase activities (pkat mg-1 protein) in stem material from COMT downregulates transgenic alfalfa[1].
References	[1]. K Parvathi, et al. Substrate Preferences of O-methyltransferases in Alfalfa Suggest New Pathways for 3-O-methylation of Monolignols. Plant J. 2001 Jan;25(2):193-202. [2]. S Maury, et al. Tobacco O-methyltransferases Involved in Phenylpropanoid Metabolism. The Different Caffeoyl-Coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferase Classes Have Distinct Substrate Specificities and Expression Patterns. Plant Physiol. 1999 Sep;121(1):215-24. [3]. Inoue, et al. Substrate Preferences of Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferases in Developing Stems of Alfalfa (Medicago Sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82.

Hazard Codes	Xi
HS Code	2918990090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%