α-Conotoxin EI
Modify Date: 2025-08-27 16:00:26
α-Conotoxin EI structure
|
Common Name | α-Conotoxin EI | ||
|---|---|---|---|---|
| CAS Number | 170663-33-9 | Molecular Weight | 2093.37000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C83H125N27O27S5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of α-Conotoxin EIα-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[1][2][3]. |
| Name | α-Conotoxin EI |
|---|---|
| Synonym | More Synonyms |
| Description | α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 187 nM (nicotinic acetylcholine α1β1γδ receptor)[3] |
| In Vitro | α-Conotoxin EI (10 µM) blocks muscle and ganglionic receptors, but less potent for the central nevous system receptor[3]. α-Conotoxin EI (10 µM) blocks the α1β1γδ receptors with a τon of 4.9 s, and blocks the α3β4 receptor with a τon of 11 s[3]. |
| In Vivo | α-Conotoxin EI (intraperitoneal injection) into mice induces muscular weakness, followed by flaccid paralysis and ultimately death[1]. |
| Molecular Formula | C83H125N27O27S5 |
|---|---|
| Molecular Weight | 2093.37000 |
| Exact Mass | 2091.78000 |
| PSA | 1002.01000 |
| ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS-NH2 |
| A-CONOTOXIN EL |
| ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS |
| RDHYPCCYHPTCNMSNPQIC-NH2 |
| H-ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS-NH2 |
| a-Conotoxin El,Conus ermineus |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: α-Conotoxin EI
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Nanjing Peptide Biotech Ltd
- China
- Product Name: α-Conotoxin EI
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Delivery: 7 Day
- Contact: jom
- Email: chenglong.fan@njpeptide.com
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