DHODH-IN-5

Modify Date: 2025-08-26 20:07:15

DHODH-IN-5 Structure
DHODH-IN-5 structure
Common Name DHODH-IN-5
CAS Number 1644156-56-8 Molecular Weight 364.44
Density N/A Boiling Point N/A
Molecular Formula C21H24N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DHODH-IN-5


DHODH-IN-5 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. DHODH-IN-5 inhibits measles virus replication, with a pMIC50 of 8.8[1].

 Names

Name DHODH-IN-5

 DHODH-IN-5 Biological Activity

Description DHODH-IN-5 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. DHODH-IN-5 inhibits measles virus replication, with a pMIC50 of 8.8[1].
Related Catalog
References

[1]. Munier-Lehmann H, et al. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH). J Med Chem. 2015 Jan 22;58(2):860-77.

 Chemical & Physical Properties

Molecular Formula C21H24N4O2
Molecular Weight 364.44
InChIKey BSNKBAPMWCMENP-UHFFFAOYSA-N
SMILES Cc1c(C(O)c2ccccc2)c(OC(C)C)nn1-c1ncc(C2CC2)cn1
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