RSK2-IN-3

Modify Date: 2023-02-23 10:02:50

RSK2-IN-3 Structure
RSK2-IN-3 structure
Common Name RSK2-IN-3
CAS Number 1627136-54-2 Molecular Weight 450.49
Density N/A Boiling Point N/A
Molecular Formula C24H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RSK2-IN-3


RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].

 Names

Name RSK2-IN-3

 RSK2-IN-3 Biological Activity

Description RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].
Related Catalog
Target

RSK2:8.3 (pIC50, ERK2-MSK1 cascade)

RSK2:9.2 (pIC50, MSK1 CTKD)

References

[1]. Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108.

 Chemical & Physical Properties

Molecular Formula C24H26N4O5
Molecular Weight 450.49