NaV1.7 inhibitor-1

Modify Date: 2025-09-10 13:07:47

NaV1.7 inhibitor-1 structure	Common Name	NaV1.7 inhibitor-1
	CAS Number	1494585-79-3	Molecular Weight	435.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₀FNO₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NaV1.7 inhibitor-1

NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].

Name	NaV1.7 inhibitor-1

Description	NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	IC50: 0.6 nM (hNaV1.7)[1]
References	[1]. Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.

Molecular Formula	C₂₃H₃₀FNO₄S
Molecular Weight	435.55
InChIKey	GFDXIUXAFNREKM-UHFFFAOYSA-N
SMILES	CC1(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CCC2(CC1)CC2

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NaV1.7 inhibitor-1
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Purity: 98.0%
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