Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NaV1.7 inhibitor-1
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1494585-79-3

1494585-79-3 structure

1494585-79-3 structure

Name: NaV1.7 inhibitor-1
Chemical Name: NaV1.7 inhibitor-1
CAS Number: 1494585-79-3
Molecular Formula: C₂₃H₃₀FNO₄S
Molecular Weight: 435.55
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2019-06-30 09:36:15
Modify Date: 2025-09-10 13:07:47
NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].

Name	NaV1.7 inhibitor-1

Description	NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	IC50: 0.6 nM (hNaV1.7)[1]
References	[1]. Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.

Molecular Formula	C₂₃H₃₀FNO₄S
Molecular Weight	435.55

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