SC-51322

Modify Date: 2025-08-26 01:50:37

SC-51322 Structure
SC-51322 structure
Common Name SC-51322
CAS Number 146032-79-3 Molecular Weight 457.93000
Density N/A Boiling Point N/A
Molecular Formula C22H20ClN3O4S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of SC-51322


SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE2) receptor (EP 1), with a pA2 of 8.1. SC-51322 has the pain-relieving effect[1].

 Names

Name 3-chloro-N'-[3-(furan-2-ylmethylsulfanyl)propanoyl]-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
Synonym More Synonyms

 SC-51322 Biological Activity

Description SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE2) receptor (EP 1), with a pA2 of 8.1. SC-51322 has the pain-relieving effect[1].
Related Catalog
Target

EP1 Receptor:8.1 (pA2)

References

[1]. Hallinan EA, et, al. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE2 antagonist and analgesic. Bioorganic & Medicinal Chemistry Letters. Feb 1994. 4(3): 509-514.

 Chemical & Physical Properties

Molecular Formula C22H20ClN3O4S
Molecular Weight 457.93000
Exact Mass 457.08600
PSA 109.11000
LogP 5.95640
InChIKey CQBVTZDISUKDSX-UHFFFAOYSA-N
SMILES O=C(CCSCc1ccco1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII

 Synonyms

hms3263n13
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