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SC-51322

Names

[ CAS No. ]:
146032-79-3

[ Name ]:
SC-51322

[Synonym ]:
hms3263n13

Biological Activity

[Description]:

SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE2) receptor (EP 1), with a pA2 of 8.1. SC-51322 has the pain-relieving effect[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Research Areas >> Neurological Disease

[Target]

EP1 Receptor:8.1 (pA2)


[References]

[1]. Hallinan EA, et, al. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE2 antagonist and analgesic. Bioorganic & Medicinal Chemistry Letters. Feb 1994. 4(3): 509-514.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H20ClN3O4S

[ Molecular Weight ]:
457.93000

[ Exact Mass ]:
457.08600

[ PSA ]:
109.11000

[ LogP ]:
5.95640

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII


Related Compounds

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