ML-243
Modify Date: 2025-08-20 17:07:07
ML-243 structure
|
Common Name | ML-243 | ||
|---|---|---|---|---|
| CAS Number | 1426576-80-8 | Molecular Weight | 260.355 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C14H16N2OS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of ML-243ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP[1]. |
| Name | (2E)-N-(4,5-Dihydro-1,3-thiazol-2-yl)-3-(4-ethylphenyl)acrylamide |
|---|---|
| Synonym | More Synonyms |
| Description | ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP[1]. |
|---|---|
| Related Catalog | |
| Target |
Breast CSCs[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C14H16N2OS |
| Molecular Weight | 260.355 |
| Exact Mass | 260.098328 |
| PSA | 70.25000 |
| LogP | 2.65 |
| Index of Refraction | 1.608 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
|
~40%
ML-243 CAS#:1426576-80-8 |
| Literature: THE BROAD INSTITUTE, INC.; GERMAIN, Andrew; MUNOZ, Benito; LEWIS, Timothy, A.; TING, Amal; YOUNGSAYE, Willmen; NAG, Partha, P.; DOCKENDORFF, Christopher; FERNANDEZ, Cristina, Victoria; DONCKELE, Etienne; MORGAN, Barbara; SKODA, Erin, M.; SHU, Byubg-Chul Patent: WO2013/32907 A1, 2013 ; Location in patent: Page/Page column 54 ; |
| (2E)-N-(4,5-Dihydro-1,3-thiazol-2-yl)-3-(4-ethylphenyl)acrylamide |
| 2-Propenamide, N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-, (2E)- |
| Streptomyces metabolite 2880 II |
| 2880-II |