ML 604086

Modify Date: 2024-01-02 18:13:09

ML 604086 structure	Common Name	ML 604086
	CAS Number	850330-18-6	Molecular Weight	508.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₂N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ML 604086

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

Name	ML604086

Description	ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Inflammation/Immunology
Target	CCR8[1][2].
References	[1]. James E. Pease, et al. Chemokine Receptors in Allergy, Inflammation, and Infectious Disease. Top Med Chem (2015) 14: 1-40. [2]. Lin Wang, et al. Antagonism of chemokine receptor CCR8 is ineffective in a primate model of asthma. Thorax 2013;68:506–512.

Molecular Formula	C₂₇H₃₂N₄O₄S
Molecular Weight	508.63

DC Chemicals Limited
China
Product Name: ML 604086
Price: $950.0/100mg $1900.0/250mg $3800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Chemical & Physical Properties