Pim-IN-22m
Modify Date: 2025-09-18 17:04:30
Pim-IN-22m structure
|
Common Name | Pim-IN-22m | ||
|---|---|---|---|---|
| CAS Number | 1405126-60-4 | Molecular Weight | 435.483 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H23F2N7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Pim-IN-22mPim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively; potently inhibits the phosphorylation of BAD (s112) in a cell line that expresses high levels of all Pim isoforms, KMS-12-BM (IC50=28 nM). |
| Name | Pim-IN-22m |
|---|
| Description | Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively; potently inhibits the phosphorylation of BAD (s112) in a cell line that expresses high levels of all Pim isoforms, KMS-12-BM (IC50=28 nM). |
|---|---|
| References | References 1. Wurz RP, et al. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5580-5590. View Related Products by Target Pim |
| Molecular Formula | C23H23F2N7 |
|---|---|
| Molecular Weight | 435.483 |
| InChIKey | BYFQNMWZRKKFRI-CABCVRRESA-N |
| SMILES | CC1CC(N)CN(c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)C1 |