Thiol-PEG5-Amine

Modify Date: 2025-09-21 12:38:30

Thiol-PEG5-Amine Structure
Thiol-PEG5-Amine structure
Common Name Thiol-PEG5-Amine
CAS Number 1347750-20-2 Molecular Weight 297.41
Density N/A Boiling Point N/A
Molecular Formula C12H27NO5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiol-PEG5-Amine


HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name HS-PEG5-CH2CH2NH2
Synonym More Synonyms

 Thiol-PEG5-Amine Biological Activity

Description HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C12H27NO5S
Molecular Weight 297.41
InChIKey CLMWLYNJZRFYHK-UHFFFAOYSA-N
SMILES NCCOCCOCCOCCOCCOCCS

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD29052169
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