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248582-03-8

248582-03-8 structure
248582-03-8 structure
  • Name: Thiol-PEG5-alcohol
  • Chemical Name: Thiol-PEG5-alcohol
  • CAS Number: 248582-03-8
  • Molecular Formula: C10H22O5S
  • Molecular Weight: 254.341
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-02-06 04:37:55
  • Modify Date: 2024-09-15 10:09:57
  • Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name Thiol-PEG5-alcohol
Synonyms 2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethanol
HS-PEG5-OH
Description Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Molecular Formula C10H22O5S
Molecular Weight 254.341

Chemsrc provides CAS#:248582-03-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 248582-03-8 | Chemsrc address: https://www.chemsrc.com/en/baike/1466465.html

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