1449390-67-3

1449390-67-3 structure

1449390-67-3 structure

Name: Thiol-PEG5-acid
Chemical Name: Thiol-PEG5-acid
CAS Number: 1449390-67-3
Molecular Formula: C₁₃H₂₆O₇S
Molecular Weight: 326.41
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:24:36
Modify Date: 2024-01-10 18:38:42
Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Thiol-PEG5-acid

Description	Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₃H₂₆O₇S
Molecular Weight	326.41