MCH(human, mouse, rat)
MCH(human, mouse, rat) structure
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Common Name | MCH(human, mouse, rat) | ||
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| CAS Number | 128315-56-0 | Molecular Weight | 2386.84000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C105H160N30O26S4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of MCH(human, mouse, rat)MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1]. |
| Name | Melanin Concentrating Hormone rat |
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| Synonym | More Synonyms |
| Description | MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1]. |
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| Related Catalog | |
| Target |
Binding IC50: 0.3 nM (MCH1R) IC50: 1.5 nM (MCH1R)[1] |
| References |
| Molecular Formula | C105H160N30O26S4 |
|---|---|
| Molecular Weight | 2386.84000 |
| Exact Mass | 2385.10000 |
| PSA | 1018.94000 |
| LogP | 6.54720 |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | T+ |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor.
Nat. Cell Biol. 12 , 267-271, (1999) Gene-knockout studies of melanin-concentrating hormone (MCH) and its effect on feeding and energy balance have firmly established MCH as an orexigenic (appetite-stimulating) peptide hormone. Here we i... |
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Molecular characterization of the melanin-concentrating-hormone receptor.
Nature 400 , 265-269, (1999) Orphan G-protein-coupled receptors (GPCRs) are cloned proteins with structural characteristics common to the GPCRs but that bind unidentified ligands. Orphan GPCRs have been used as targets to identif... |
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Investigation of the feeding effects of melanin concentrating hormone on food intake--action independent of galanin and the melanocortin receptors.
Brain Res. 846 , 164-170, (1999) Melanin concentrating hormone (MCH) is recognised as a hypothalamic appetite stimulant. The mechanism of action of MCH is undetermined largely due to lack of identification of hypothalamic MCH recepto... |
| MFCD00080193 |
| Melanin Concentrating Hormone,human,mouse |
| Melanin concentrating hormone,human,mouse,rat |
- DC Chemicals Limited
- China
- Product Name: MCH(human, mouse, rat)
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: MCH (human, mouse, rat)
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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