171869-93-5

171869-93-5 structure

Name: α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
Chemical Name: α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
CAS Number: 171869-93-5
Molecular Formula: C₇₉H₁₁₀F₃N₂₁O₂₁S
Molecular Weight: 1778.907
Catalog: Research Areas Metabolic Disease
Create Date: 2021-07-05 10:42:07
Modify Date: 2024-01-14 20:05:23
α-Melanocyte-Stimulating Hormone (MSH), amide TFA is an endogenous neuropeptide, with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC), acts as an endogenous melanocortin receptor 4 (MC4R) agonist[1][2].

Name	α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
Synonyms	N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide trifluoroacetate (1:1) L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)

Description	α-Melanocyte-Stimulating Hormone (MSH), amide TFA is an endogenous neuropeptide, with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC), acts as an endogenous melanocortin receptor 4 (MC4R) agonist[1][2].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor
Target	MC4R[2]
References	[1]. Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9.