MCH(human, mouse, rat)
MCH(human, mouse, rat) structure
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Common Name | MCH(human, mouse, rat) | ||
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| CAS Number | 128315-56-0 | Molecular Weight | 2386.84000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C105H160N30O26S4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor.
Nat. Cell Biol. 12 , 267-271, (1999) Gene-knockout studies of melanin-concentrating hormone (MCH) and its effect on feeding and energy balance have firmly established MCH as an orexigenic (appetite-stimulating) peptide hormone. Here we identify MCH as the ligand for the orphan receptor SLC-1. Th... |
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Molecular characterization of the melanin-concentrating-hormone receptor.
Nature 400 , 265-269, (1999) Orphan G-protein-coupled receptors (GPCRs) are cloned proteins with structural characteristics common to the GPCRs but that bind unidentified ligands. Orphan GPCRs have been used as targets to identify novel transmitter molecules. Here we describe the isolati... |
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Investigation of the feeding effects of melanin concentrating hormone on food intake--action independent of galanin and the melanocortin receptors.
Brain Res. 846 , 164-170, (1999) Melanin concentrating hormone (MCH) is recognised as a hypothalamic appetite stimulant. The mechanism of action of MCH is undetermined largely due to lack of identification of hypothalamic MCH receptors. We designed in vivo and in vitro studies to further cha... |